美國(guó)凱斯西儲(chǔ)大學(xué)2025年博士后招聘(膜蛋白結(jié)構(gòu)生物學(xué)與生理學(xué))
Postdoctoral Position in Membrane Protein Structural Biology and Physiology
Date Posted: Posted on 3 June 2025
Location: United States (US)
Case Western Reserve University
The laboratory of Dr. Nami Tajima at Case Western Reserve University School of Medicine invites applications for a postdoctoral researcher to investigate the molecular mechanisms of ligand-gated ion channel signaling complexes. We seek a highly motivated, creative, and collaborative individual with expertise in electrophysiology, structural biology, or related fields.
Research Focus
Our lab is broadly interested in understanding:
The regulatory mechanisms of ion channels involved in fundamental brain function and neurological disorders.
The signaling networks and protein-protein interactions that govern synaptic transmission.
Structure-based drug discovery targeting ion channel complexes.
We employ a multidisciplinary approach that integrates Cryo-EM, X-ray crystallography, electrophysiology, molecular and cellular biology, biochemistry, and biophysics.
Our lab has full access to state-of-the-art structural biology facilities, including a Glacios equipped with Seletrix Energy filter and Falcon IV DED camera,Titan Krios with BioQuantum K3, and Volta Phase Plate, Aquilos II Cryo-FIB with CLEM system, and Tecnai T12&TF20.
Qualifications
Candidates must hold (or be close to completing) a Ph.D. obtained within the past three years in a relevant field such as structural biology, biophysics, neuroscience, or molecular biology. A strong publication record and prior experience in one or more of the following areas is highly desirable:
Electrophysiology
Biochemistry or protein purification
Cryo-EM or X-ray crystallography
Neuroscience or cell biology
Mass spectrometry
In vitro and in vivo fluorescence imaging
How to Apply
Interested applicants should send the following materials to Dr. Nami Tajima at [Please click the Apply button for the link or address]: (1) a cover letter describing research interests and career goals, (2) a current CV, and (3) contact information for 2–3 references.
We look forward to hearing from passionate researchers eager to explore the structure and function of ion channels in the brain.
Follow the link for more details:
https://www.the-tajima-lab-at-cwru.com/
https://physiology.case.edu/people/faculty/nami-tajima/
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