澳大利亞阿德萊德大學2024年招聘博士后（實體癌的新型免疫療法）
阿德萊德大學（The University of Adelaide），簡稱“阿大”，是澳大利亞歷史上第三所最古老的大學，2024年QS世界大學排名89位。該校是澳大利亞南澳大利亞州首府阿德萊德的研究型高等學府，也是砂巖學府之一，21世紀學術(shù)聯(lián)盟、澳大利亞八校聯(lián)盟、英聯(lián)邦大學協(xié)會成員。
Grant-Funded Researcher (A)
The University of Adelaide
Fixed term, full time position available for 24 months.
An opportunity exists for a talented postdoctoral researcher to join the T Cell Immunotherapy Lab (PI Dr Mara Zeissig) to work on novel immunotherapies for the treatment of solid cancers. The applicant should have experience in cellular immunology or cancer immunotherapy.
The Lab's research is focused on understanding how cancers evade the immune system to identify new ways to enhance response to immunotherapy. In particular, we work on cancers that are addicted to the oncogene KRAS such as lung, colorectal and pancreatic cancers. We utilise a range of tools including genetically engineered preclinical models of cancer, analysis of immune cell subsets, single-cell profiling and molecular biology techniques. We also harness large-scale genetic screening using CRISPR-Cas9 technology to find previously unknown targets and mechanisms that regulate response to immunotherapy.
About the project:
In this project, the candidate will be involved in an exciting new discovery project using CRISPR/Cas9 screens to identify new genes that improve T cell persistence and anti-tumour responses. New drug targets identified in the screens will be characterised in vitro and in vivo to assess the effects on tumour growth, immune infiltration and response to immunotherapy.
To be successful you will need:
PhD in Cancer Biology, Immunology or Cancer Immunotherapy (or near completion).
Excellent academic record and research experience that has resulted in publications, conference papers or reports
Experience with cellular immunology, flow cytometry, cell culture and molecular/biochemical techniques
Ability to contribute to a diverse and collaborative team environment and manage time effectively
High quality written and oral communication skills
Applications close 11:55pm, 19 September 2024.
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